Discover and read the best of Twitter Threads about #EducationintheTimeofCOVID

@JenniferSpicer4

1/#COVID19 cohort study in ICU patients showing lower mortality rate than prior reports

Thx @EmoryMedicine students @justalisongrace & @AdamJamnik (creators), @chung_yg & @cg_coleman (editors) & ID fellow @DBhamidipatee (reviewer)

#EducationInTheTimeofCOVID #COVIDfoam

2/Here's a link to the pre-print (i.e. not peer-reviewed yet) from @EmoryMedicine faculty Sara Auld, @colleenkraftmd, @alfherrom, @hey_its_max, @jestjac, @gsmartinmd, and many more

doi.org/10.1101/2020.0…

3/And a link to our webpage that hosts the literature summaries from our #EmoryID fellows and visuals from our medical students
med.emory.edu/departments/me…

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Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/How does pre-symptomatic transmission contribute to #COVID19 spread in nursing facilities?

Thx @EmoryMedicine MS3s @_mkline_ & Jeff Rosenthal (creators), @chung_yg & @cg_coleman(editors) & @EmoryDeptofMed ID fellow Aaron Kofman (review)

#EducationInTheTimeofCOVID #COVIDfoam

2/This is a nice follow up to the prior visual abstract we created on an earlier version of the study that you can see here

https://twitter.com/JenniferSpicer4/status/1247505809128505344

Interestingly, you can see that most of the "asymptomatic" individuals were actually "pre-symptomatic" as many of us suspected

3/Here's a link to this new article in @NEJM
nejm.org/doi/10.1056/NE…

And a link to our webpage that hosts the literature summaries from our #EmoryID fellows and visuals from our medical students
med.emory.edu/departments/me…

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/ This study documents patients who tested positive for SARS-CoV-2 after an initial negative test

Thx @EmoryMedicine MS3s @ariellevaldez & Eman Hijab (creators), @an_xiao_ & @cg_coleman (editors), &@EmoryDeptofMed ID fellow @DBhamidipatee (review)

#EducationInTheTimeOfCOVID

2/ It's unclear from this report if this is truly "reactivation." The authors mention that patients had symptoms, but it's unclear if these are new symptoms or persistent symptoms.

Is this really reactivation? Or just persistent infection? Or re-infection?

3/ It's all a little unclear, but it will be interesting to see more data

A positive PCR test just detects viral nucleic acid; it doesn't confirm actual live, replicating virus is still present. We don't know if these patients are still infectious (& they're likely not)

Read 6 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/ Can antibody testing help predict true case fatality rate for #COVID19?

Thx @EmoryMedicine M3s Timothy Arleo & @mlmargol (creators), M4s @tylerdau &@cg_coleman (editors) & Emory ID fellow Aaron Kofman (review)

#EducationInTheTimeOfCOVID #COVID19FOAM

2/ This study has multiple limitations making it difficult to know the accuracy of the results.

It will be interesting to see the results after the peer review process.

3/ Here's a link to the pre-print (i.e. not peer-reviewed yet)
doi.org/10.1101/2020.0…

Link to our #EmoryID fellows' scholar blog w/ other lit summaries by our ID fellows; plus visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

How well do alcohol-based hand rub formulations inactivate SARS-CoV-2?

Thx @EmoryMedicine students @emilyslovern & @sims_hershey (creators), @an_xiao_& @cg_coleman (editors) & @EmoryDeptofMed ID fellow @DanielSGraciaa (reviewer)

#EducationInTheTimeOfCOVID #COVID19FOAM #COVID19

A link to the article @CDC_EIDjournal by @AnnikaKratzel & @StephaniePfaen1
doi.org/10.3201/eid260…

Link to our #EmoryID fellows' scholar blog w/ other lit summaries by our ID fellows; plus visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

Please tag additional authors of this work!

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

High IL-6 may be predictive of respiratory failure in #COVID19

Thx @EmoryMedicine @EmoryMSTP students @ariellevaldez & @careyjans (creators), MS4s @tylerdau & @cg_coleman (editors), & @EmoryDeptofMed ID fellow @Dr_AmyKacin (reviewer)

#EducationInTheTimeOfCOVID #COVIDFOAM

Here's a link to the pre-print (i.e. not peer-reviewed yet):
doi.org/10.1101/2020.0…

And the link to our #EmoryID fellows' scholar blog w/ other lit summaries by our ID fellows; plus visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

Tag the authors if you know their Twitter handles. I couldn't find them :)

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

The ISTH recommends prophylactic anticoagulation for #COVID19 inpatients

Thx @EmoryMedicine students @andre_kerri & @justalisongrace (creators), @tylerdau @cg_coleman (editors) & @EmoryDeptofMed ID fellow @alfherrom (review)

#EducationInTheTimeOfCOVID #COVID19FOAM

Here's the link to the article
doi.org/10.1111/jth.14…

And the link to our #EmoryID fellows' scholar blog w/ other lit summaries by our ID fellows; plus visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

@RoyKhalife89 - would love to hear your thoughts on this!

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Jennifer Spicer, MD, MPH

@JenniferSpicer4

Mice developed Abs against a recombinant protein of the SARS-CoV-2 spike protein - promising for vaccine development

Thx Emory MS4 creators @ZaynahAlam1, @hklin3, & @rebeccasteinberg; editors @cg_coleman & @tylerdau; & reviewer ID fellow @Dr_AmyKacin

#EducationInTheTimeOfCOVID

Here's a link to the article in @nature
nature.com/articles/s4142…

And the link to our #EmoryID fellows' scholar blog w/ other lit summaries, visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

*Note: typo in the text that we are fixing, but wanted to get this out there for everyone

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/Recent article on remdesivir for #COVID19. More summaries to come soon on more recent data.

Thx @EmoryMedicine MS3s @an_xiao_ & @chung_yg (creators), MS4s @tylerdau & @cg_coleman (editors) & #ID fellow @Dr_AmyKacin (review)!

#EducationInTheTimeOfCOVID #COVID19FOAM

2/This is not a randomized controlled trial, which is the data that we really need. Trials ongoing with results soon.

3/Here's the link to this article in @NEJM
doi.org/10.1056/NEJMoa…

And the link to our #EmoryID fellows' scholar blog w/ other lit summaries, visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

What was the impact of various public health interventions on #COVID19 in Wuhan, China?

Thx @EmoryMedicine M3s @SimonCohen617 & @blokolog9 (creators), @tylerdau & @cg_coleman (editors) & @EmoryDeptofMed #ID fellow JessH_A (review)!

#EducationInTheTimeOfCOVID #COVID19FOAM

Here's a link to the article in @JAMANetworkOpen
jamanetwork.com/journals/jama/…

And the link to our #EmoryID fellows' scholar blog w/ other lit summaries, visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

Here's the actual link - sorry, that prior link was to the commentary on the article:
jamanetwork.com/journals/jama/…

Read 3 tweets

Kimberly D. Manning, MD

@gradydoctor

1/
#ZOOMintheTimeofCOVID

The more we’re required to meet virtually, the better we need to get at it. I’ve seen some GREAT pro-tips on the technical features of @zoom_us.

But.

I’ve also appreciated some little things that could make #zoomlife easier.

Let's discuss, mmkay?

2/
First, get yourself situated:

Take a pre-login bio break.
Have water/coffee within reach.
Need to take notes? Have what you need handy—phone, tablet, it’s up to you.*

*Confession: Sometimes I have my desktop/other laptop for notes and searches--but don't tell anyone.🤫

3/
Signal vs. noise:

Many “big deal” lectures are becoming virtual. Internet can be shaky depending on location in your house or when too many devices are plugged in. Secure a quiet, reliable space in advance.*

*Note: Quiet is challenging with kids & pets--plan if you can.

Read 15 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/Type I Interferons may be effective for #COVID19, but more in vitro info needed before moving to human studies

Thx @EmoryMedicine students Morgan Schafer & @mlmargol (creators), @cg_coleman & @tylerdau (editors) & ID fellow @SamInSilico (reviewer)

#EducationInTheTimeofCOVID

2/Not too surprising given that this is the biological role of Type I interferons in our body (i.e. our bodies' own antivirals).

Interferons are used for treatment in other diseases but definitely have significant side effects given their lack of specificity.

3/And here's a link to the pre-print (i.e. not peer-reviewed yet):
doi.org/10.1101/2020.0…

And the link to our #EmoryID fellows' scholar blog w/ other lit summaries, visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/This retrospective study did not show any benefit of hydroxychloroquine in patients w/ #COVID19

Thx @EmoryMedicine M3s @AGangavelli & @sverma46 (creators), @chung_yg & @cg_coleman(editors) & Emory ID fellow @Dr_AmyKacin (peer review)

#EducationInTheTimeOfCOVID #COVID19FOAM

2/We are still waiting results of the randomized controlled trials for definitive evidence, but this additional data continues to suggest that HCQ is not helpful for #COVID19

3/And here's a link to the pre-print (i.e. not peer-reviewed yet): doi.org/10.1101/2020.0……

And the link to our #EmoryID fellows' scholar blog w/ other lit summaries, visual abstracts & infographics created by our medical students. scholarblogs.emory.edu/covid19roundup/

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/
What should breastfeeding look like in COVID (+) mothers? Short answer: we aren't sure.

Thx @EmoryMedicine MS3s @sims_hershey & @emilyslovern (creators), @cg_coleman & @tylerdau (editors) & Peds ID fellow @Mehganteherani (peer reviewer).

#EducationInTheTimeOfCOVID

2/
Long answer:
While there is no evidence yet of SARS-CoV-2 transmission through breast milk, recommendations for breastfeeding mothers w/ #COVID19 depend on clinical course.

3/
Here's the link to the article w/ guidance from the Italian Society of Neonatology:
doi.org/10.1111/mcn.13…

And the link to our #EmoryID fellows' scholar blog w/ other lit summaries, visual abstracts & infographics created by our medical students.
scholarblogs.emory.edu/covid19roundup/

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/A new study shows sputum & fecal specimens PCR+ for SARS-CoV-2 even after NP samples are negative

Thx @EmoryMedicine M3s Shubham Patel & @an_xiao_ (creators), MS4 Caroline Coleman (editor) & @EmoryDeptofMed ID fellow @Dr_AmyKacin (peer review)
#EducationInTheTimeOfCOVID

2/ A major limitation of this study is that it detects nucleic acid via PCR, which doesn't necessarily indicate the presence of LIVE virus.

3/ Here's the link to the study in @AnnalsofIM :
annals.org/aim/fullarticl…

And the link to our #EmoryID fellows' scholar blog with other literature summaries and visual abstracts & infographics created by our medical students.
scholarblogs.emory.edu/covid19roundup/

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/
A cohort study assessing HCQ+azithro in hospitalized patients w/ #COVID19 showed no clear clinical benefit

Thx @EmoryMedicine MS3s Timothy Arleo & @sims_hershey (creators), @cg_coleman & @tylerdau (editors), & #EmoryID fellow @Boghuma (peer review)

#EducationInTheTimeOfCOVID

2/
This study had no control group, so a randomized-controlled trial is still needed; however, these results contradict prior studies showing substantial benefits with this combination and should call into question the results of that study.

3/
Here's the link to the article: sciencedirect.com/science/articl…

And here's the link to the #EmoryID fellows' scholar blog with other article summaries plus our visual abstracts & infographics by @EmoryMedicine students:
scholarblogs.emory.edu/covid19roundup/

Read 3 tweets

Jennifer Spicer, MD, MPH

@JenniferSpicer4

1/ @EmoryMedicine M4 @cg_coleman organized med students to create visual educational materials on #COVID19 for our residents to maintain #EducationintheTimeofCOVID

Follow karen.ll.law (Insta), me (Twitter)

Thanks @EmoryDeptofMed ID & CCM fellows for peer reviewing!

2/ Here's our first post from yesterday.

Let us know what you want to learn & please correct any mistakes you see! #COVIDfoam

@VarunPhadke2 @Armstrws @CarlosdelRio7 @karenlawmd @Dr_AmyKacin @MDdreamchaser @gradydoctor @BSchwartzinSF @BonuraErin @Emory_MedMicro @Ahmed_HBabiker

@DanicaRockney @JHaydek - share with the residents too!

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Discover and read the best of Twitter Threads about #EducationintheTimeofCOVID

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Discover and read the best of Twitter Threads about #EducationintheTimeofCOVID

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