Discover and read the best of Twitter Threads about #DrugDevelopment
Most recents (10)
In May 2019, Dr. @rschilsky & I co-chaired the #AAADV19 Workshop Plenary Session "Decentralized #ClinicalTrials: The Future is Now." An incredible group of panelists from academia, industry, govt, & patient #advocacy šdiscussed the rationale, challenges, & opportunities of DCTs. 
No one knew yet that the #COVID19 #pandemic was just around the corner. In Mar 2020, FDA released a guidance on conduct of #clinicaltrials during the pandemic: fda.gov/media/136238/dā¦, & colleagues wrote about the impact on #OncTwitter trials: ncbi.nlm.nih.gov/pmc/articles/Pā¦. /2
FDA has now released a draft guidance on decentralized #clinicaltrials for drugs, biological products, & devices covering #telehealth, remote assessments, consent, shipping of IP, & more: fda.gov/media/167696/dā¦. #MedTwitter #regulatory #drugdevelopment
1/ $PVCTās Modernized #SmallMolecule #RoseBengal: A #DrugSubstance, and #ActivePharmaceuticalIngredient for 21st Century #DrugDevelopment. A THREAD.
2/ āEveryoneā seems to know or understand #RoseBengal, but do they (you) really?
3/ #RoseBengal is a small molecule (i.e., <1,000 Daltons*), but a āheavyā one at 973.67 Da or g/mol. It is heavy because of its four iodides, which comprise 52% of its molecular weight.
1/ A THREAD on what $PVCT achieved in 2022. #event #discovery #milestone #milepost. #rosebengal #rosebengalsodium.
3/ $PVCT #clinical and #research collaborators made 6 presentations at 5 medical conferences about PV-10 for different cancers. #ENETS22 #AACR22 #ASCO22 #ISOO2022 #melanomabridge. #presentations. #rosebengal #rosebengalsodium.
#Genomics is a rapidly growing field of #science that has revolutionized the way we understand #biology.
It has #applications in diverse fields. From #healthcare and #biotechnology to #climatechange, genomics is leading to some of the most exciting and world-changing discoveries in science and #medicine like:
1. Predicting Disease Risk:š
Genomics can detect diseases long before symptoms present themselves. Early #diagnosis of a disease can significantly increase the chances of successful treatments like #cancer, #diabetes, #autism, etc.
Genomics can detect diseases long before symptoms present themselves. Early #diagnosis of a disease can significantly increase the chances of successful treatments like #cancer, #diabetes, #autism, etc.
Daily Bookmarks to GAVNetĀ 11/09/2021 greeneracresvaluenetwork.wordpress.com/2021/11/09/daiā¦
The shifting sands of āgain-of-functionā research
nature.com/articles/d4158ā¦
#GainOfFunction #ResearchMethodology #ethics #narrative #consequences
nature.com/articles/d4158ā¦
#GainOfFunction #ResearchMethodology #ethics #narrative #consequences
Structure of a āpromiscuousā protein will help scientists design better drugs
phys.org/news/2021-11-pā¦
#GutProtein #MolecularStructure #DrugDevelopment #DrugAbsorption #ResearchResults
phys.org/news/2021-11-pā¦
#GutProtein #MolecularStructure #DrugDevelopment #DrugAbsorption #ResearchResults
Syngene is delighted to share that we are part of Fortune Indiaās Top 100 Wealth Creators list for 2021.
The criteria involved being a listed company with a 5-year CAGR of 7.5% plus in terms of market cap, revenue &profit (2017-21).
#FortuneIndia #Syngene #FortuneList #CDMO
1/5
The criteria involved being a listed company with a 5-year CAGR of 7.5% plus in terms of market cap, revenue &profit (2017-21).
#FortuneIndia #Syngene #FortuneList #CDMO
1/5
Those incurring a net loss in any of the 5 fiscals (2016-20) were filtered out. The final 100 were based on firms having revenues of Rs 300 crores or more in FY20.
2/5
2/5
Key to our success has been our growing clientele who regard us more as a strategic partner with flexibility to work across a spectrum of clients -MNCs to start-ups. We also have a consistent client retention rate of 90%.
#strategicpartnership #clientele #USA #Europe #Japan
3/5
#strategicpartnership #clientele #USA #Europe #Japan
3/5
(1/13) Please RT: our first #tweetorial!
Here's a š§µon our new paper which is also my 1st time being (joint) last authorāļø
Congrats to all, especially superstar med student @LuszczakSabina!
#AcademicTwitter @AcademicChatter @OpenAcademics #womeninSTEM
nature.com/articles/s4159ā¦
Here's a š§µon our new paper which is also my 1st time being (joint) last authorāļø
Congrats to all, especially superstar med student @LuszczakSabina!
#AcademicTwitter @AcademicChatter @OpenAcademics #womeninSTEM
nature.com/articles/s4159ā¦
(2/13) In #prostatecancer cell lines & human tissue, co-targeting #PIM & #PI3K #kinases seems promising!
We reckon ~20% of prostate cancer patients could benefit from this approach in future & these tend to be the sicker patients.
Scroll for #science!
nature.com/articles/s4159ā¦
We reckon ~20% of prostate cancer patients could benefit from this approach in future & these tend to be the sicker patients.
Scroll for #science!
nature.com/articles/s4159ā¦
šNEW BLOG POST ALERT šØā£ā£
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Click our link to read our latest blog post on COVID-19 treatments and where weāre at with data. ā£ā£ā£ā£
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thesciencesocial.com/2020/05/05/covā¦
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Give it a read and get back to us with your questions and comments āØ
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Click our link to read our latest blog post on COVID-19 treatments and where weāre at with data. ā£ā£ā£ā£
ā£ā£
thesciencesocial.com/2020/05/05/covā¦
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Give it a read and get back to us with your questions and comments āØ
#science #sciencecommunicationā£ #scicomm #drug #drugdevelopment #treatment #covid #covid19 #viruses #virus #plasma #blood #plasmadonation #blooddonation #social #scienceexperiments #scienceinsta #instascience
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Thread: I am getting tons of msgs from fellows since a few recent talks at @hopkinskimmel, @SocTransOnc Fellows Forum, etc, + Twitter. I am happy to hear from all of you, esp the many people interested in #regulatory science. But many similar Qs, so here goes w/ resources!
@hopkinskimmel @SocTransOnc The #FDA_ASCOFellowsDay is a 1d workshop for #hematology & #oncology fellows in last yr (+ lim # of next to last yr) of training. It happens 2x/yr (fall & spring) on FDA campus in MD & 1x/yr at @ASCO Annual Mtg (1/2 day on Fri am). Applications for #ASCO20 one will open soon. 2/X
@hopkinskimmel @SocTransOnc @ASCO Our next one at the FDA campus is coming up on 3/10/20 (already full). This is a screenshot w/ high-level overview of it, and here's the link where you'll find application instructions for the next one once it opens in a few wks: asco.org/training-educaā¦ 3/X
I will now proceed to go on a #tweetrant / #tweetorial with regards to #Pharmaceutical #biotech pricing (focus on #cancer).
Very timely, also see @WSJ wsj.com/articles/big-pā¦ on price hikes.
For the record, no #COI / #FCOI. Feel free to contribute to this discussion.
Very timely, also see @WSJ wsj.com/articles/big-pā¦ on price hikes.
For the record, no #COI / #FCOI. Feel free to contribute to this discussion.
Lets look at the problem from the @PhRMA / business perspective. And lets suppose you are a wonderful company, started by wonderful people who just want to make the world a better place (I know, not real, but stay with me for a minute).
You start with a great idea / or pipeline platform and start selling this concept to #VC #VentureCapital, and lets assume that this is actually a really good idea. What is the needed return on investment to make this worth while. A: further R&D must exceed the cost of capital.
