Discover and read the best of Twitter Threads about #BoxOfNails
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Mitochondrial dysfunctions cause telomere attrition, while telomere damage leads to the reprogramming of mitochondrial biosynthesis and mitochondrial dysfunctions, which have important implications in aging and diseases.
#BoxOfNails
#BagOfBeans
#Spiroplasma
#AirborneAIDS
#BoxOfNails
#BagOfBeans
#Spiroplasma
#AirborneAIDS
Mitochondrial & telomere are mostly studied independently. However, SARS Let'er R.I.P. has made clear that there are intimate links between mitochondria, telomeres, and telomerase subunits. There's an erratic looping mechanism when one of these goes wrong.
en.wikipedia.org/wiki/MRNA_surv…
en.wikipedia.org/wiki/MRNA_surv…
We know senescent cells contribute to body dysfunction (ageing). We know telomere shortening is a recognized cause of cellular senescence. Several conditions associated with normal ageing are precipitated by accelerated telomere dysfunction.
#BagOfBeans
ncbi.nlm.nih.gov/pmc/articles/P…
#BagOfBeans
ncbi.nlm.nih.gov/pmc/articles/P…
This is a great graphic to understand CoVs #BoxOfNails flawed reproduction process. The initial infected cells are epithelium, but secondary infection adjacent cells can be any type of cells.
“The effect is more pronounced for the N protein of wild-type SARS-CoV-2 than that of the Omicron variant and other human coronaviruses.” This study only applied research for lung epithelium cells so if there’s persistent GI infection then this effect will occur with Omikron.
The infected epithelium cells are prevented from signalling danger and undergoing apoptosis (natural cell death) is delayed. The infected cell is held hostage to throw more boxes of nails from the roof (reproduction).
#SARSsexSlaves
#SARSsexSlaves
