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#BlackInChem Day 2: Although I am an analytical chemist at heart, over the years, I've drifted so much into biology that I am now building a career as a malariologist😅.
For #BlackInBiological, let me tell you about PfcPRS, the protein that was at the center of my PhD research.
For #BlackInBiological, let me tell you about PfcPRS, the protein that was at the center of my PhD research.
The image above is a representation of the structure of the human version of the protein (this will be important later 😀). It was solved by the Schimmel group at @scrippsresearch using X-ray diffraction (analytical chem, FTW!). nature.com/articles/natur… (ncbi.nlm.nih.gov/pmc/articles/P…)
So what is PfcPRS? It is the (c)ytoplasmic (p)rolyl t(R)NA (s)ynthetase in (P)lasmodium (f)alciparum, the deadliest malaria parasite.
It catalyzes the formation of proline building blocks for protein synthesis.
It catalyzes the formation of proline building blocks for protein synthesis.
