Discover and read the best of Twitter Threads about #Appetite
Most recents (12)
Here, a triple agonist that interacts with GLP-1, neuropeptide Y1&Y2 receptors, regulated insulin secretion in rat and human pancreatic islets, promoted insulin-independent Y1-R-mediated glucose uptake in rat muscle tissue ex vivo and reduced food intake and body weight in rats. 
- Mechanisms underlying long-term sustained weight loss and glycemic normalization after obesity surgery include changes in gut hormone levels, including glucagon-like peptide 1 (GLP-1) and peptide YY (PYY).
- PYY1–36 is a gut hormone that binds to the Y1-R in pancreatic islets and central nervous system nuclei that control appetite regulation in the brain including the brainstem area postrema and nucleus tractus solitarius, where it has an orexigenic effect.
The findings of this one suggest that dietary carbohydrate and exercise may generate independent and interactive effects on the plasma metabolome, resulting in the generation of distinct metabolic phenotypes that may influence appetite regulation and perhaps energy intake.
- This study aimed to determine the interactive effects of carbohydrate and exercise on the plasma hormonal and metabolite responses and explore potential mediators of exercise-induced changes in appetite and energy intake across nutritional states.
- In a randomised-crossover fashion, 12 male participants completed four study visits that involved the consumption of a control (water) or carbohydrate beverage (75 g maltodextrin, 300 kcal), followed by a 30-minute rest or exercise session (75% V'O2max on a cycle ergometer).
This one failed to find an effect of long-term (24 weeks) daily administration of intranasal insulin at 40IU once daily on food intake, appetite, and weight in older adults with a mean age of 65.5 years, either with or without type 2 diabetes.
- A null effect of 24 weeks daily administration of 40 I.U. of intranasal insulin once daily on food intake, appetite, and weight in older adults was observed.
- Similarly, there were no differences in the effect of intranasal insulin when comparing men to women, obese to lean participants, and diagnosis of type 2 diabetes.
In this one, a phenotype-tailored lifestyle intervention was associated with further improvements in measures of body composition and triglycerides compared with a standard lifestyle intervention.
- This 12-week, single-centre non-randomised proof-of-concept clinical trial included men and women aged 18–65 years with a body mass index (BMI) greater than 30 without history of any bariatric procedure, and current use of any medication known to affect weight.
- Participants were assigned to their intervention based on their period of enrollment.
The findings of this one may suggest that individuals with lower habitual exercise and/or higher fasting concentrations of PYY are more likely to show a compensatory increase in energy intake for energy expended in exercise.
- The present study aimed to identify predictors of post-exercise energy intake and compensation in healthy adults following a single 45-min aerobic exercise bout.
- Individuals with lower habitual exercise and/or higher fasting concentrations of PYY ate more after an acute exercise bout, even after accounting for the energy expended during the exercise bout.
This one suggests that just one single meal lower in protein content may lead to increases in daily total caloric consumption in order to experience the same level of fullness and hunger suppression.
- "Indeed, we found that the average macronutrient composition of the SSMD (Self-Selected Meal Day) meals was lower in both protein and carbohydrate, and higher in fat, than the study diet...
"...In addition, the daily caloric intake on the SSMD was 14% higher (or an average of an extra 262 total daily calories, P<0.001) than baseline daily intake...
This one found that the timing of calorie distribution (breakfast/dinner) may have no effect in total daily energy expenditure, resting metabolic rate, improvements in weight loss, or measures of cardiometabolic risk, but it may affect hunger.
This is pretty cool, so...
- This was a 4-week randomized crossover isocaloric and eucaloric controlled feeding trial, comparing morning loaded (45%:35%:20% kcal at breakfast:lunch:dinner) versus evening loaded (20%:35%:45% kcal at breakfast:lunch:dinner) calorie intake.
This study explored the effect of three different modes of resistance training on appetite hormones, cardiometabolic and anthropometric measures in males with obesity.
- 44 males with obesity were randomized to traditional resistance training (TRT, n = 11), circuit resistance training (CRT, n = 11), interval resistance training (IRT, n = 11) or control (C, n = 11) groups.
- All resistance training groups received 50 min of supervised training per session, three days per week, for 12 weeks.
This one found that whilst glycine, both alone and within a multivariate model, can estimate appetite response to both water and whey protein beverage consumption, a large proportion of variance in appetite response remains unexplained.
Most biomarkers, when assessed in isolation, were found to be poor predictors of appetite response, therefore they're likely of utility only in combination with Visual Analogue Scales (VAS) and energy intake (EI).
"our current study demonstrated that glycine was the most prominent biomarker of appetite response, investigated in a whey protein model in a cohort of women with overweight/obesity."
New paper in #Appetite about masculinity stress & red meat consumption.
👉 High masculinity stress men are more likely to believe that eating meat will ↗️ their masculinity and, consequently, are more likely to purchase red meat
👉Affirming one's masculinity ↘️ red meat choice
👉 High masculinity stress men are more likely to believe that eating meat will ↗️ their masculinity and, consequently, are more likely to purchase red meat
👉Affirming one's masculinity ↘️ red meat choice
About the general conclusion.
1/2
10 year old #boy. Loss of weight, very high #appetite, ⬆️thirst, urination - 6 months. LFT - AST 1200, ALT 2300, ALP, Bil, INR - normal. Wilsons, autoimmune -ve. IgG - 2xULN. CTscan - massive hepatomegaley. #Liver #biopsy 👇 Rare! ❓ #livertwitter #MedTwitter
10 year old #boy. Loss of weight, very high #appetite, ⬆️thirst, urination - 6 months. LFT - AST 1200, ALT 2300, ALP, Bil, INR - normal. Wilsons, autoimmune -ve. IgG - 2xULN. CTscan - massive hepatomegaley. #Liver #biopsy 👇 Rare! ❓ #livertwitter #MedTwitter
2/2
HbA1c is 15.2🔥Uncontrolled #diabetes with hepatic #glycogenosis, diastase treatment, glycogen disappears! [Mauriac Syndrome] 6 months intensive #nutrition & #insulin, Repeat biopsy - #normal liver!
Scary presentation in a child, but simple #treatment
#medicine #pathology
HbA1c is 15.2🔥Uncontrolled #diabetes with hepatic #glycogenosis, diastase treatment, glycogen disappears! [Mauriac Syndrome] 6 months intensive #nutrition & #insulin, Repeat biopsy - #normal liver!
Scary presentation in a child, but simple #treatment
#medicine #pathology
for those who missed my @aberdeen_ucu talk today on #sugar, #breakfast, #health & #appetite, a wee thread on the fascinating properties of sugar...
full talk (poor sound qual) can be found here:
1/21
full talk (poor sound qual) can be found here:
1/21
#sugar is demonised in the media, literally described as "evil". myths include: its addictive, causes cravings, makes you hungry, makes you overeat, makes you gain weight.
current #publichealth guidelines target reducing sugar
2/21
current #publichealth guidelines target reducing sugar
2/21
#breakfast is touted the "most important" meal of the day. what does "important" mean?
breakfast is the highest #sugar meal of the day so a good meal to target to reduce total sugar.
breakfast = complex to define, but broadly breaks the overnight fast (break-fast) 3/21
breakfast is the highest #sugar meal of the day so a good meal to target to reduce total sugar.
breakfast = complex to define, but broadly breaks the overnight fast (break-fast) 3/21
